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Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels
Macroautophagy is thought to protect against apoptosis, however underlying mechanisms are poorly understood. We examined how autophagy affects canonical death receptor-induced mitochondrial outer membrane permeabilization (MOMP) and apoptosis. MOMP occurs at variable times in a population of cells a...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992854/ https://ncbi.nlm.nih.gov/pubmed/24685133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.036 |
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