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Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase

The search for novel compounds of relevance to the treatment of diseases caused by trypanosomatid protozoan parasites continues. Screening of a large library of known bioactive compounds has led to several drug-like starting points for further optimisation. In this study, novel analogues of the mono...

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Main Authors: Walton, Jeffrey G A, Jones, Deuan C, Kiuru, Paula, Durie, Alastair J, Westwood, Nicholas J, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047706/
https://ncbi.nlm.nih.gov/pubmed/21275055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000442
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