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Does Huntingtin play a role in selective macroautophagy?
The accumulation of protein aggregates in neurons appears to be a basic feature of neurodegenerative disease. In huntington disease (HD), a progressive and ultimately fatal neurodegenerative disorder caused by an expansion of the polyglutamine repeat within the protein huntingtin (Htt), the immediat...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047613/ https://ncbi.nlm.nih.gov/pubmed/20703094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.17.12718 |
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