Huntingtin Functions as a Scaffold for Selective Macroautophagy

Selective macroautophagy is an important protective mechanism against diverse cellular stresses. In contrast to the well-characterized starvation-induced autophagy, the regulation of selective autophagy is largely unknown. Here, we demonstrate that Huntingtin, the Huntington’s disease gene product,...

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Pubblicato in:Nat Cell Biol
Autori principali: Rui, Yan-Ning, Xu, Zhen, Patel, Bindi, Chen, Zhihua, Chen, Dongsheng, Tito, Antonio, David, Gabriela, Sun, Yamin, Stimming, Erin F., Bellen, Hugo, Cuervo, Ana Maria, Zhang, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344873/
https://ncbi.nlm.nih.gov/pubmed/25686248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3101
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