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Does Huntingtin play a role in selective macroautophagy?

The accumulation of protein aggregates in neurons appears to be a basic feature of neurodegenerative disease. In huntington disease (HD), a progressive and ultimately fatal neurodegenerative disorder caused by an expansion of the polyglutamine repeat within the protein huntingtin (Htt), the immediat...

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Dades bibliogràfiques
Autor principal: Steffan, Joan S
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047613/
https://ncbi.nlm.nih.gov/pubmed/20703094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.17.12718
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