Nalaganje...
Asp(433) in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca(2+) block
A constriction formed by the crossing of the second transmembrane domains of ASIC1, residues G432 to G436, forms the narrowest segment of the pore in the crystal structure of chicken ASIC1, presumably in the desensitized state, suggesting that it constitutes the “desensitization gate” and the “selec...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047608/ https://ncbi.nlm.nih.gov/pubmed/21357733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010576 |
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