RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

Therapeutics that discriminate between the genetic makeup of normal cells and tumour cells are valuable for treating and understanding cancer. Small molecules with oncogene-selective lethality may reveal novel functions of oncoproteins and enable the creation of more selective drugs1. Here we descri...

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Detalhes bibliográficos
Main Authors: Yagoda, Nicholas, von Rechenberg, Moritz, Zaganjor, Elma, Bauer, Andras J., Yang, Wan Seok, Fridman, Daniel J., Wolpaw, Adam J., Smukste, Inese, Peltier, John M., Boniface, J. Jay, Smith, Richard, Lessnick, Stephen L., Sahasrabudhe, Sudhir, Stockwell, Brent R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047570/
https://ncbi.nlm.nih.gov/pubmed/17568748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05859
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