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Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells
An emerging treatment option for chronic lymphocytic leukemia (CLL) is to make cytotoxic immune cells express a chimeric antigen receptor (CAR) that recognizes specific surface molecules on CLL cells. Here an mRNA coding for an anti-CD19 CAR was transfected into the NK-92 cell line by electroporatio...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047414/ https://ncbi.nlm.nih.gov/pubmed/19147228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2008.11.024 |
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