Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity

Multiple natural killer (NK) cell-based anticancer therapies are currently under development. Here, we compare the efficiency of genetically modified NK-92 cells expressing chimeric antigen receptors (CARs) at killing NK cell-resistant B-lymphoid leukemia cells to the antibody-dependent cell-mediate...

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Detalhes bibliográficos
Main Authors: Boissel, Laurent, Betancur-Boissel, Monica, Lu, Weiquan, Krause, Daniela S, Van Etten, Richard A, Wels, Winfried S, Klingemann, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881109/
https://ncbi.nlm.nih.gov/pubmed/24404423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26527
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