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Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size
OBJECTIVE: We examined the role of Rictor/mammalian target of rapamycin complex 2 (mTORC2), a key component of the phosphotidylinositol-3-kinase (PI3K)/mTORC2/AKT signaling pathway, in regulating both β-cell mass and function. RESEARCH DESIGN AND METHODS: Mice with β-cell–specific deletions of Ricto...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046843/ https://ncbi.nlm.nih.gov/pubmed/21266327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1194 |
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