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Stepwise or Linear Decrease in Penetrance of Type 1 Diabetes With Lower-Risk HLA Genotypes Over the Past 40 Years
OBJECTIVE: The objective of this study was to test if the proportion of new-onset diabetic subjects with the HLA-DR3/4-DQB1*0302 genotype is decreasing over time. RESEARCH DESIGN AND METHODS: We analyzed HLA class II genotype frequencies over time in two large populations with type 1 diabetes diagno...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Diabetes Association
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046823/ https://ncbi.nlm.nih.gov/pubmed/21307077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1419 |
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