Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes

We assessed the effects of non-HLA gene polymorphisms on the risk of islet autoimmunity (IA) and progression to type 1 diabetes in the Diabetes Autoimmunity Study in the Young. A total of 1,743 non-Hispanic, white children were included: 861 first-degree relatives and 882 general population children...

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Main Authors: Steck, Andrea K., Wong, Randall, Wagner, Brandie, Johnson, Kelly, Liu, Edwin, Romanos, Jihane, Wijmenga, Cisca, Norris, Jill M., Eisenbarth, George S., Rewers, Marian J.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2012
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282811/
https://ncbi.nlm.nih.gov/pubmed/22315323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1228
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