Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.

Retroviral vectors, designated handicapped, are described. These are genetically defective viruses that allow transfer of nonselectable genes under the transcriptional control of internal promoters. The basic handicapped vector (pHHAM) is derived from Harvey, Abelson, and Moloney murine retroviruses...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Hawley, R G, Covarrubias, L, Hawley, T, Mintz, B
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1987
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2406
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