Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.

Retroviral vectors, designated handicapped, are described. These are genetically defective viruses that allow transfer of nonselectable genes under the transcriptional control of internal promoters. The basic handicapped vector (pHHAM) is derived from Harvey, Abelson, and Moloney murine retroviruses...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Hawley, R G, Covarrubias, L, Hawley, T, Mintz, B
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1987
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2406
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