Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.

Retroviral vectors, designated handicapped, are described. These are genetically defective viruses that allow transfer of nonselectable genes under the transcriptional control of internal promoters. The basic handicapped vector (pHHAM) is derived from Harvey, Abelson, and Moloney murine retroviruses...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Hawley, R G, Covarrubias, L, Hawley, T, Mintz, B
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1987
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031683/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2406
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