Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

INTRODUCTION: Mutational inactivation of the FBXW7/hCDC4 tumor suppressor gene (TSG) is common in many cancer types, but infrequent in breast cancers. This study investigates the presence and impact of FBXW7/hCDC4 promoter methylation in breast cancer. METHODS: FBXW7/hCDC4-β expression and promoter...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Akhoondi, Shahab, Lindström, Linda, Widschwendter, Martin, Corcoran, Martin, Bergh, Jonas, Spruck, Charles, Grandér, Dan, Sangfelt, Olle
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046450/
https://ncbi.nlm.nih.gov/pubmed/21122106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2788
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker