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Neuroantigen-Specific CD8+ Regulatory T-Cell Function is Deficient During Acute Exacerbation of Multiple Sclerosis
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS). MS is thought to be T-cell-mediated, with prior research predominantly focusing on CD4+ T-cells. There is a high prevalence of CNS-specific CD8+ T-cell responses in MS patients and healthy subjects...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046327/ https://ncbi.nlm.nih.gov/pubmed/21257291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2010.12.003 |
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