Induction of Regulatory T-cells from Memory T-cells Is Perturbed During Acute Exacerbation of Multiple Sclerosis

Regulatory T-cells (Tregs) are vital for maintaining immunological self-tolerance, and the transcription factor FOXP3 is considered critical for their development and function. Peripheral Treg induction may significantly contribute to the total Treg pool in healthy adults, and this pathway may be en...

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Publicado en:Clin Immunol
Main Authors: Mohiuddin, Imran H., Pillai, Vinodh, Baughman, Ethan J., Greenberg, Benjamin M., Frohman, Elliot M., Crawford, Michael P., Sinha, Sushmita, Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902765/
https://ncbi.nlm.nih.gov/pubmed/27154631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2016.05.001
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