Neuroantigen-Specific CD8+ Regulatory T-Cell Function is Deficient During Acute Exacerbation of Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS). MS is thought to be T-cell-mediated, with prior research predominantly focusing on CD4+ T-cells. There is a high prevalence of CNS-specific CD8+ T-cell responses in MS patients and healthy subjects...

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Hlavní autoři: Baughman, Ethan J., Mendoza, Jason P., Ortega, Sterling B., Ayers, Chris L., Greenberg, Benjamin M., Frohman, Elliot M., Karandikar, Nitin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046327/
https://ncbi.nlm.nih.gov/pubmed/21257291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2010.12.003
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