RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

RhoA is a small guanosine-5’-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell–cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin blistering. To analyze RhoA function in vivo, we generated mice with a keratinocyt...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jackson, Ben, Peyrollier, Karine, Pedersen, Esben, Basse, Astrid, Karlsson, Richard, Wang, Zhipeng, Lefever, Tine, Ochsenbein, Alexandra M., Schmidt, Gudula, Aktories, Klaus, Stanley, Alanna, Quondamatteo, Fabio, Ladwein, Markus, Rottner, Klemens, van Hengel, Jolanda, Brakebusch, Cord
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Cell Biology 2011
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046057/
https://ncbi.nlm.nih.gov/pubmed/21209320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0859
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