Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

Cell migration is commonly accompanied by protrusion of membrane ruffles and lamellipodia. In two-dimensional migration, protrusion of these thin sheets of cytoplasm is considered relevant to both exploration of new space and initiation of nascent adhesion to the substratum. Lamellipodium formation...

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Main Authors: Steffen, Anika, Ladwein, Markus, Dimchev, Georgi A., Hein, Anke, Schwenkmezger, Lisa, Arens, Stefan, Ladwein, Kathrin I., Margit Holleboom, J., Schur, Florian, Victor Small, J., Schwarz, Janett, Gerhard, Ralf, Faix, Jan, Stradal, Theresia E. B., Brakebusch, Cord, Rottner, Klemens
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817791/
https://ncbi.nlm.nih.gov/pubmed/23902686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.118232
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