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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

RhoA is a small guanosine-5’-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell–cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin blistering. To analyze RhoA function in vivo, we generated mice with a keratinocyt...

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Autors principals: Jackson, Ben, Peyrollier, Karine, Pedersen, Esben, Basse, Astrid, Karlsson, Richard, Wang, Zhipeng, Lefever, Tine, Ochsenbein, Alexandra M., Schmidt, Gudula, Aktories, Klaus, Stanley, Alanna, Quondamatteo, Fabio, Ladwein, Markus, Rottner, Klemens, van Hengel, Jolanda, Brakebusch, Cord
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046057/
https://ncbi.nlm.nih.gov/pubmed/21209320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0859
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