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Role of the Hsp90/Hsp70-Based Chaperone Machinery in Making Triage Decisions When Proteins Undergo Oxidative and Toxic Damage
The Hsp90/Hsp70-based chaperone machinery plays a well established role in signaling protein function, trafficking and turnover. A number of recent observations also support the notion that Hsp90 and Hsp70 play key roles in the triage of damaged and aberrant proteins for degradation via the ubiquiti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046050/ https://ncbi.nlm.nih.gov/pubmed/20404045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2009.009250 |
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