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Role of the Hsp90/Hsp70-Based Chaperone Machinery in Making Triage Decisions When Proteins Undergo Oxidative and Toxic Damage

The Hsp90/Hsp70-based chaperone machinery plays a well established role in signaling protein function, trafficking and turnover. A number of recent observations also support the notion that Hsp90 and Hsp70 play key roles in the triage of damaged and aberrant proteins for degradation via the ubiquiti...

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Detalhes bibliográficos
Main Authors: Pratt, William B., Morishima, Yoshihiro, Peng, Hwei-Ming, Osawa, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046050/
https://ncbi.nlm.nih.gov/pubmed/20404045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2009.009250
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