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Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis
This report examines the molecular mechanism by which high-fidelity DNA polymerases select nucleotides during the replication of an abasic site, a non-instructional DNA lesion. This was accomplished by synthesizing several unique 5-substituted indolyl 2′-deoxyribose triphosphates and defining their...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045600/ https://ncbi.nlm.nih.gov/pubmed/20952399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq925 |
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