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A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs

Chromatin immunoprecipitation (ChIP) followed by high throughput sequencing (ChIP-seq) is rapidly becoming the method of choice for discovering cell-specific transcription factor binding locations genome wide. By aligning sequenced tags to the genome, binding locations appear as peaks in the tag pro...

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書目詳細資料
Main Authors: Rye, Morten Beck, Sætrom, Pål, Drabløs, Finn
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045577/
https://ncbi.nlm.nih.gov/pubmed/21113027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1187
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