Loading...

Structure Determination of Glycogen Synthase Kinase-3 from Leishmania major and Comparative Inhibitor Structure-Activity Relationships with Trypanosoma brucei GSK-3

Glycogen synthase kinase-3 (GSK-3) is a drug target under intense investigation in pharmaceutical companies and constitutes an attractive piggyback target for eukaryotic pathogens. Two different GSKs are found in trypanosomatids, one about 150 residues shorter than the other. GSK-3 short (GeneDB: Tb...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ojo, Kayode K., Arakaki, Tracy L., Napuli, Alberto J., Inampudi, Krishna K., Keyloun, Katelyn R., Zhang, Li, Hol, Wim G.J., Verlinde, Christophe L.M.J., Merritt, Ethan A., Van Voorhis, Wesley C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045540/
https://ncbi.nlm.nih.gov/pubmed/21195115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.12.009
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!