Glycogen Synthase Kinase 3 Is a Potential Drug Target for African Trypanosomiasis Therapy

Development of a safe, effective, and inexpensive therapy for African trypanosomiasis is an urgent priority. In this study, we evaluated the validity of Trypanosoma brucei glycogen synthase kinase 3 (GSK-3) as a potential drug target. Interference with the RNA of either of two GSK-3 homologues in bl...

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Detaylı Bibliyografya
Asıl Yazarlar: Ojo, Kayode K., Gillespie, J. Robert, Riechers, Aaron J., Napuli, Alberto J., Verlinde, Christophe L. M. J., Buckner, Frederick S., Gelb, Michael H., Domostoj, Mathias M., Wells, Susan J., Scheer, Alexander, Wells, Timothy N. C., Van Voorhis, Wesley C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Susceptibility
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565902/
https://ncbi.nlm.nih.gov/pubmed/18644955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00364-08
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