Structure Determination of Glycogen Synthase Kinase-3 from Leishmania major and Comparative Inhibitor Structure-Activity Relationships with Trypanosoma brucei GSK-3

Glycogen synthase kinase-3 (GSK-3) is a drug target under intense investigation in pharmaceutical companies and constitutes an attractive piggyback target for eukaryotic pathogens. Two different GSKs are found in trypanosomatids, one about 150 residues shorter than the other. GSK-3 short (GeneDB: Tb...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ojo, Kayode K., Arakaki, Tracy L., Napuli, Alberto J., Inampudi, Krishna K., Keyloun, Katelyn R., Zhang, Li, Hol, Wim G.J., Verlinde, Christophe L.M.J., Merritt, Ethan A., Van Voorhis, Wesley C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045540/
https://ncbi.nlm.nih.gov/pubmed/21195115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.12.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados