Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors

BACKGROUND: Monocyte-derived macrophages contribute to atherosclerotic plaque formation. Therefore, manipulating macrophage function could have significant therapeutic value. The objective of this study was to determine transduction efficiency of two HIV-based lentiviral vector configurations as del...

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Bibliographic Details
Main Authors: Leyva, Francisco J, Anzinger, Joshua J, McCoy, J Philip, Kruth, Howard S
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045310/
https://ncbi.nlm.nih.gov/pubmed/21281514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-13
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