Native Low-Density Lipoprotein Uptake by Macrophage Colony-Stimulating Factor–Differentiated Human Macrophages Is Mediated by Macropinocytosis and Micropinocytosis

OBJECTIVE: To examine the pinocytotic pathways mediating native low-density lipoprotein (LDL) uptake by human macrophage colony-stimulating factor–differentiated macrophages (the predominant macrophage phenotype in human atherosclerotic plaques). METHODS AND RESULTS: We identified the kinase inhibit...

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Detalhes bibliográficos
Main Authors: Anzinger, Joshua J., Chang, Janet, Xu, Qing, Buono, Chiara, Li, Yifu, Leyva, Francisco J., Park, Bum-Chan, Greene, Lois E., Kruth, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170564/
https://ncbi.nlm.nih.gov/pubmed/20634472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.210849
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