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Fluid-Phase Pinocytosis of Native Low Density Lipoprotein Promotes Murine M-CSF Differentiated Macrophage Foam Cell Formation

During atherosclerosis, low-density lipoprotein (LDL)-derived cholesterol accumulates in macrophages to form foam cells. Macrophage uptake of LDL promotes foam cell formation but the mechanism mediating this process is not clear. The present study investigates the mechanism of LDL uptake for macroph...

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Detalhes bibliográficos
Main Authors: Barthwal, Manoj K., Anzinger, Joshua J., Xu, Qing, Bohnacker, Thomas, Wymann, Matthias P., Kruth, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594233/
https://ncbi.nlm.nih.gov/pubmed/23536783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058054
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