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Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions

The uptake of lipoproteins by macrophages is a critical step in the development of atherosclerotic lesions. Cultured monocyte-derived macrophages take up large amounts of native LDL by receptor-independent fluid-phase pinocytosis, either constitutively or in response to specific activating stimuli,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buono, Chiara, Anzinger, Joshua J., Amar, Marcelo, Kruth, Howard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673852/
https://ncbi.nlm.nih.gov/pubmed/19363293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35548
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