Fluid-Phase Pinocytosis of Native Low Density Lipoprotein Promotes Murine M-CSF Differentiated Macrophage Foam Cell Formation

During atherosclerosis, low-density lipoprotein (LDL)-derived cholesterol accumulates in macrophages to form foam cells. Macrophage uptake of LDL promotes foam cell formation but the mechanism mediating this process is not clear. The present study investigates the mechanism of LDL uptake for macroph...

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Main Authors: Barthwal, Manoj K., Anzinger, Joshua J., Xu, Qing, Bohnacker, Thomas, Wymann, Matthias P., Kruth, Howard S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594233/
https://ncbi.nlm.nih.gov/pubmed/23536783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058054
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