Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization

Activation of Nrf2 by covalent modifications that release it from its inhibitor protein Keap1 has been extensively documented. In contrast, covalent modifications that may regulate its action after its release from Keap1 have received little attention. Here we show that CREB-binding protein induced...

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Autori principali: Kawai, Yumiko, Garduño, LaKisha, Theodore, Melanie, Yang, Jianqi, Arinze, Ifeanyi J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045017/
https://ncbi.nlm.nih.gov/pubmed/21196497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208173
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