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Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization

Activation of Nrf2 by covalent modifications that release it from its inhibitor protein Keap1 has been extensively documented. In contrast, covalent modifications that may regulate its action after its release from Keap1 have received little attention. Here we show that CREB-binding protein induced...

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Détails bibliographiques
Auteurs principaux: Kawai, Yumiko, Garduño, LaKisha, Theodore, Melanie, Yang, Jianqi, Arinze, Ifeanyi J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045017/
https://ncbi.nlm.nih.gov/pubmed/21196497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208173
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