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Multiple Nuclear Localization Signals Function in the Nuclear Import of the Transcription Factor Nrf2

Nuclear factor erythroid 2-related factor 2 (Nrf2) mediates the transcriptional response of cells to oxidative stress and is translocated into the nucleus following, or concomitant with, its activation by electrophiles or reactive oxygen species. The mechanism of its translocation into the nucleus i...

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Detalhes bibliográficos
Main Authors: Theodore, Melanie, Kawai, Yumiko, Yang, Jianqi, Kleshchenko, Yuliya, Reddy, Sekhar P., Villalta, Fernando, Arinze, Ifeanyi J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276363/
https://ncbi.nlm.nih.gov/pubmed/18238777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709040200
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