N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein: IMPLICATIONS FOR NEURODEGENERATION IN ALZHEIMER DISEASE

Synaptic loss, which strongly correlates with the decline of cognitive function, is one of the pathological hallmarks of Alzheimer disease. N-cadherin is a cell adhesion molecule essential for synaptic contact and is involved in the intracellular signaling pathway at the synapse. Here we report that...

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Main Authors: Ando, Koichi, Uemura, Kengo, Kuzuya, Akira, Maesako, Masato, Asada-Utsugi, Megumi, Kubota, Masakazu, Aoyagi, Nobuhisa, Yoshioka, Katsuji, Okawa, Katsuya, Inoue, Haruhisa, Kawamata, Jun, Shimohama, Shun, Arai, Tetsuaki, Takahashi, Ryosuke, Kinoshita, Ayae
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045016/
https://ncbi.nlm.nih.gov/pubmed/21177868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158477
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