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Generation of a New Form of Human PrP(Sc) in Vitro by Interspecies Transmission from Cervid Prions

Prion diseases are infectious neurodegenerative disorders that affect humans and animals and that result from the conversion of normal prion protein (PrP(C)) into the misfolded prion protein (PrP(Sc)). Chronic wasting disease (CWD) is a prion disorder of increasing prevalence within the United State...

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書誌詳細
主要な著者: Barria, Marcelo A., Telling, Glenn C., Gambetti, Pierluigi, Mastrianni, James A., Soto, Claudio
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045004/
https://ncbi.nlm.nih.gov/pubmed/21209079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198465
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