Novel Insight into the Mechanism of the Vitamin K Oxidoreductase (VKOR): ELECTRON RELAY THROUGH Cys(43) AND Cys(51) REDUCES VKOR TO ALLOW VITAMIN K REDUCTION AND FACILITATION OF VITAMIN K-DEPENDENT PROTEIN CARBOXYLATION

Podobné jednotky

• The Vitamin K Oxidoreductase Is a Multimer That Efficiently Reduces Vitamin K Epoxide to Hydroquinone to Allow Vitamin K-dependent Protein Carboxylation
  Autor: Rishavy, Mark A., a další
  Vydáno: (2013)
• VKOR paralog VKORC1L1 supports vitamin K–dependent protein carboxylation in vivo
  Autor: Lacombe, Julie, a další
  Vydáno: (2018)
• A new model for vitamin K-dependent carboxylation: The catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine
  Autor: Rishavy, Mark A., a další
  Vydáno: (2004)
• The Vitamin K-dependent Carboxylase Generates γ-Carboxylated Glutamates by Using CO(2) to Facilitate Glutamate Deprotonation in a Concerted Mechanism That Drives Catalysis
  Autor: Rishavy, Mark A., a další
  Vydáno: (2011)
• Vitamin K Oxygenation, Glutamate Carboxylation, and Processivity: Defining the Three Critical Facets of Catalysis by the Vitamin K–Dependent Carboxylase
  Autor: Rishavy, Mark A., a další
  Vydáno: (2012)