β-Catenin Activation Synergises with PTEN Loss to Cause Bladder Cancer Formation

Although deregulation of the Wnt signalling pathway has been implicated in urothelial cell carcinoma (UCC), the functional significance is unknown. To test its importance, we have targeted expression of an activated form of β-catenin to the urothelium of transgenic mice using Cre-Lox technology (Uro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ahmad, Imran, Morton, Jennifer P, Singh, Lukram Babloo, Radulescu, Sorina M, Ridgway, Rachel A, Patel, Satish, Woodgett, James, Winton, Douglas J, Taketo, Makato Mark, Wu, Xue-Ru, Leung, Hing Y, Sansom, Owen J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044461/
https://ncbi.nlm.nih.gov/pubmed/20818428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.399
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia