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The Role of Apolipoprotein E in Alzheimer’s Disease

The ε4 allele of apolipoprotein E (APOE) is the major genetic risk factor for Alzheimer’s disease (AD). Although there have been numerous studies attempting to elucidate the underlying mechanism for this increased risk, the manner in which apoE4 influences AD onset and progression has yet to be prov...

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Bibliografiske detaljer
Main Authors: Kim, Jungsu, Basak, Jacob M., Holtzman, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044446/
https://ncbi.nlm.nih.gov/pubmed/19679070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.06.026
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