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Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms

Alzheimer’s disease (AD) is clinically characterized with progressive memory loss and cognitive decline. Synaptic dysfunction is an early pathological feature that occurs prior to neurodegeneration and memory dysfunction. Mounting evidence suggests that aggregation of amyloid-β (Aβ) and hyperphospho...

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Pubblicato in:Mol Cells
Autori principali: Kim, Jaekwang, Yoon, Hyejin, Basak, Jacob, Kim, Jungsu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Molecular and Cellular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255096/
https://ncbi.nlm.nih.gov/pubmed/25358504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.0248
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