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Roles of Apolipoprotein E in Alzheimer’s Disease and Other Neurological Disorders
Apolipoprotein E (ApoE) is a 299 amino acid protein encoded by the APOE gene. Three common polymorphisms in the APOE gene, ε2, ε3, and ε4, result in single amino changes in the ApoE protein. The APOEε2, ε3, and ε4 alleles strongly and dose-dependently alter the likelihood of developing Alzheimer’s d...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132088/ https://ncbi.nlm.nih.gov/pubmed/21349439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(10)70325-2 |
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