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Intronic delay is essential for oscillatory expression in the segmentation clock

Proper timing of gene expression is essential for many biological events, but the molecular mechanisms that control timing remain largely unclear. It has been suggested that introns contribute to the timing mechanisms of gene expression, but this hypothesis has not been tested with natural genes. On...

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Bibliographische Detailangaben
Hauptverfasser: Takashima, Yoshiki, Ohtsuka, Toshiyuki, González, Aitor, Miyachi, Hitoshi, Kageyama, Ryoichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044385/
https://ncbi.nlm.nih.gov/pubmed/21300886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014418108
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