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Intronic delay is essential for oscillatory expression in the segmentation clock

Proper timing of gene expression is essential for many biological events, but the molecular mechanisms that control timing remain largely unclear. It has been suggested that introns contribute to the timing mechanisms of gene expression, but this hypothesis has not been tested with natural genes. On...

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Detalhes bibliográficos
Main Authors: Takashima, Yoshiki, Ohtsuka, Toshiyuki, González, Aitor, Miyachi, Hitoshi, Kageyama, Ryoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044385/
https://ncbi.nlm.nih.gov/pubmed/21300886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014418108
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