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Intronic delay is essential for oscillatory expression in the segmentation clock

Proper timing of gene expression is essential for many biological events, but the molecular mechanisms that control timing remain largely unclear. It has been suggested that introns contribute to the timing mechanisms of gene expression, but this hypothesis has not been tested with natural genes. On...

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Autors principals: Takashima, Yoshiki, Ohtsuka, Toshiyuki, González, Aitor, Miyachi, Hitoshi, Kageyama, Ryoichiro
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044385/
https://ncbi.nlm.nih.gov/pubmed/21300886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014418108
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