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Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy

To define alterations of neuronal connectivity that occur during motor neuron degeneration, we characterized the function and structure of spinal circuitry in spinal muscular atrophy (SMA) model mice. SMA motor neurons show reduced proprioceptive reflexes that correlate with decreased number and fun...

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Detalhes bibliográficos
Main Authors: Mentis, George Z., Blivis, Dvir, Liu, Wenfang, Drobac, Estelle, Crowder, Melissa E., Kong, Lingling, Alvarez, Francisco J., Sumner, Charlotte J., O'Donovan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044334/
https://ncbi.nlm.nih.gov/pubmed/21315257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.032
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