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Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling

Glypican-5 (GPC5) is one of the six members of the glypican family. It has been previously reported that GPC5 stimulates the proliferation of rhabdomyosarcoma cells. In this study, we show that this stimulatory activity of GPC5 is a result of its ability to promote Hedgehog (Hh) signaling. We have p...

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Détails bibliographiques
Auteurs principaux: Li, Fuchuan, Shi, Wen, Capurro, Mariana, Filmus, Jorge
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044117/
https://ncbi.nlm.nih.gov/pubmed/21339334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008087
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