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Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease
MEP1A, which encodes the α subunit of meprin metalloproteinases, is a susceptibility gene for inflammatory bowel disease (IBD), and decreased intestinal meprin-α expression is associated with enhanced IBD in humans. Mice lacking meprin α (α knockout, αKO) have more severe colitis induced by dextran...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043644/ https://ncbi.nlm.nih.gov/pubmed/21071511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00504.2009 |
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