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Meprin A impairs epithelial barrier function, enhances monocyte migration, and cleaves the tight junction protein occludin

Meprin metalloproteases are highly expressed at the luminal interface of the intestine and kidney and in certain leukocytes. Meprins cleave a variety of substrates in vitro, including extracellular matrix proteins, adherens junction proteins, and cytokines, and have been implicated in a number of in...

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Detalhes bibliográficos
Main Authors: Bao, Jialing, Yura, Renee E., Matters, Gail L., Bradley, S. Gaylen, Shi, Pan, Tian, Fang, Bond, Judith S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761208/
https://ncbi.nlm.nih.gov/pubmed/23804454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00179.2012
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